Fido-Vite is very safe. No dog food is totally immune from dogs having allergies to it. This is also the case with Fido-Vite, but we have done our best to avoid ingredients that would cause allergies. No one ingredient makes up more than 15% of Fido-Vite. We have had several reports of dogs and cats ripping open a bag of Fido-Vite and gorging themselves on Fido-Vite with no major problems.